China (Mainland)
Isoliquiritigenin CAS NO.961-29-5
- Min.Order: 25 Kilogram
- Payment Terms: L/C,T/T
- Product Details
Keywords
- Isoliquiritigenin
Quick Details
- ProName: Isoliquiritigenin
- CasNo: 961-29-5
- Molecular Formula: C15H12O4
- Appearance: Yellow powder
- Application: Action and Uses Isoliquiritigenin is a...
- DeliveryTime: 3 days
- PackAge: 25kg/drum
- Port: beijing
- ProductionCapacity: 100000 Metric Ton/Day
- Purity: 98%
- Storage: Stored in a cool and dry well-closed c...
- Transportation: by air or sea
- LimitNum: 25 Kilogram
Superiority
Product Name Isoliquiritigenin Latin Name Isoliquiritigenin Molecular Formula C15H12O4 Molecular Weight 256 CAS NO 961-29-5
Details
Product Description Product Name Isoliquiritigenin Latin Name Isoliquiritigenin Molecular Formula C15H12O4 Molecular Weight 256 CAS NO 961-29-5 Appearance White powder Product Content ≥98% Analytical Method HPLC Productigin Glycyrrhiza uralensis Fisch.; Glycyrrhiza inflata Bat.; Glycyrrhiza glabra L. Action Uses Isoliquiritigenin is a natural flavonoid isolated from licorice, shallot bean sprouts. The effect of isoliquiritigenin on cell proliferation cell cycle progression was examined in the A549 human lung cancer cell line. Isoliquiritigenin significantly inhibited the proliferation of lung cancer cells in a dose- time-dependent manner. Flow cytometric analysis demonstrated that isoliquiritigenin restrained the cell cycle progression at G2/M phase. Further examinations using cDNA arrays real-time quantitative RT-PCR revealed that isoliquiritigenin enhanced the expression of p21CIP1/WAF1, a universal inhibitof cyclin-dependent kinases. These results suggest that isoliquiritigenin will be a promising agent fuse in chemopreventive therapeutics against lung cancer. |